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I have the 428XD and i bought this rather than the 4280 because
a) I can get it ISF'd in the future
b) it has square corners rather than smooth ones (found on 4280)
In my opinion the extra 200-300 pounds is worth it purely for the ISF calibration BUT if you don't intend to get it ISF'd and are happy with smooth corners then save some money and go for the 4280XD as i believe the processing engine is exactly the same for both models.