Try to connect it to the TV, it does sound like a driver issue or compatibility issue with the USB hub.
Do you some details about your PC, especially the motherboard and GPU ?
As I said above, it requires support of the DisplayPort Alt Mode (or Thunderbolt 3) which is fairly common in most types of PCs but the desktop market is lagging behind as usual and it isn't well supported there yet.
There's no USB port on that graphics card and I don't see mention of it on that motherboard. Given that the only dedicated video output is an HDMI 1.4 connection it's clear video wasn't a priority for MSI. Does your CPU have integrated graphics?