If you have no NTSC DVDs in your collection (for example), nor any such intention, then it isn't an issue for you.
In my opinion (only) though:
a) excluding oneself from any NTSC material is limiting; even if it isn't the major part of one's collection, there are occasional instances where a better version of a film, say, or a much better DVD transfer, is only available in an NTSC territory. Bear in mind, NTSC (or 60hz) is not confined to region 1.
b) if one therefore does intend to use (even a limited spread of) NTSC material, then it is absolutely always better to display it (or any other standard) at its native frequency or an exact integer multiple of it; in other words, 60hz at 60, 120, 180 etc; 50hz at 50, 100, 150 etc. Any non-integer conversion of frequency (e.g. by a scaler, HTPC, whatever) inevitably must introduce temporal blurring, at least, and in all probability, other processing artefacts, too. In other words, degrading the signal to a much greater degree than, say, routing the video signal via an AV amplifier.