m7ds

Chlorzoxazone (INN) is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort. It can also be administered for acute pain in general and for tension headache (muscle contraction headache). It acts on the spinal cord by depressing reflexes. It is sold under the brand names Lorzone, Paraflex and Muscol and in combination form as Parafon Forte, a combination of chlorzoxazone and acetaminophen (paracetamol). Possible side effects include dizziness, lightheadedness, malaise, nausea, vomiting, and liver dysfunction. Used with acetaminophen it has added risk of hepatotoxicity.It is available as a generic medication.Like metaxalone, its mechanism of action is still in question. It is believed that metaxalone works by altering serotonin levels and acting as a mild MAO inhibitor. The mechanism of action of chlorzoxazone is thought to act on Gaba-A & B receptors and voltage-gated calcium channels to a degree. General central nervous system depression is the only currently accepted aspect to its medical benefits. Elucidation of the exact mechanism of action is ongoing but there is limited study due to the existence of more effective, safe muscle relaxants (ex. diazepam, cyclobenzaprine, tizanidine), greatly limiting the potential benefit of identifying novel compounds which share chlorzoxazone's mechanism of action.

View More On Wikipedia.org
  1. Dr.Rock

    Re-positioning Mission M7DS bipoles

    Hi, In my 5.1 system (Mission M72 mains, M72c2 centre, M7DS bipole surrounds), I used to have my surrounds on the side walls in-line with MPS and high up to the ceiling (I turned the speakers upside down as per recommendation if they're being placed close to the ceiling). I'm soon to be moving...
  2. benjitb

    Mission M7DS - Any good

    Im looking at this model below 2nd hand. I would apprechiate any input: Mission M7DS Bipole (rear) speakers. They are could finish my surround setup (I've got MA BX2's & Centre), i've been trying to get some MA bi/du pole ones but they are a little pricey for me for now. They are 2nd hand...
  3. T

    Mission m7ds placing them in ideal position.

    I have mission md7s b&w 603s2, LCR6 s2 now the b&w's are fine there in position but the missions i don't have a clue where to place. I've just finished decorating the room for a dedicated cinema room 3.5m long and 2.2m wide The sofa is on the back wall and I Am unsure if to put the missions...
  4. Dr.Rock

    Positioning of Mission M7DS dipole speakers

    Hi, My room has gone through rearrangement, which means that my 5.1 home cinema speakers need repositioning. The pair of Mission M7DS dipole surround speakers are going on the rear wall, up to the ceiling and upturned (recommended that they're upturned if placed close to the ceiling). My...
  5. Dr.Rock

    Mission M7DS bipole positioning for 5.1

    The living room's has been re-arranged, which means my HC speaker are changing position. Does anyone know where's the best place to set up my Mission M7DS surround bipole speakers in a 5.1 system? Should they be on the side wall or back wall? And is there a minimum distance they should be...
  6. Dr.Rock

    How far shoulf Mission M7DS

    I have a pair of Mission M7DS rear surround speakers from a long while back. They're bipolar. I had a re-arrangement of my living room, which means the speakers need repositioning. Does anyone know if these speakers are better suited on the rear wall behind the listerner, or on the side wall...
  7. R

    Positioning of Mission M7Ds

    Anyone got these, if so any tips on positioning. For 5.1 should they be on side walls or rear walls and how high from ceiling. Thanks.
  8. F

    recommend standmount m7ds replacements?

    Can anyone recommend some standmount speakers (would prefer bi / tri pole) to replace my wall mounted m7ds speakers? I'm looking at spending £750 all in (4 x speakers & stands and cabling) Thanks
  9. N

    Any stands available for Mission M7DS?

    Hi, I've just moved into a new flat and need to position my Mission M7DS rear speakers. Unfortunately I can't mount them on the walls for various reasons so I've been looking for stands to mount them on without any luck... Anyone have any suggestions? Thanks.
  10. funkyspider

    Kef HST2001 or Mission M7DS ?

    Kef HTS2001 or Mission M7DS ? Both second hand and available for roughly the same price (Kefs are older) These will be mounted on the back wall, the sofa is pretty much against that wall. Used mainly for a 5.1 system, with occasional audio through them. The house is a semi so these won't be...
  11. G

    MISSION m7ds & m7c1 centre speaker - Oppinions please!

    Option 1. I have been offered the above for £100. Doing a search on this forum suggests that they are pretty old speakers. They will be powered by a denon AVR-1507. Are they still a good buy at this price? Option 2. Should I go for a Mission M7C2 for £60 and get some 77DS surrounds when they...
  12. Matt

    Replacing M7DS bipoles with boofshelf speakers

    I am in the process of decorating the living room and had planned to have my M7DS bipoles up near the ceiling along the back wall that the large sofa would sit against. The TV would be in an alcolve oposite and to the right of the chimney breast. This would mean the front speakers would be not...
  13. J

    Help me to mounted Mission M7DS in my living room

    I'm going to set up 5.1 home theater in my living room.I've Mission M70i series which include M7ds Bipolar surround. I plan to mount M7ds on side wall becasue back side of sofa doesn't has wall..!! Speaker cable will go from ceiling to this bipolar. Due to my living room is poor layout..If I...
  14. stevos

    Mission m7ds - Speaker Stands

    A couple of years ago i demo'ed a replacement centre speaker at sevenoaks, who had the m7ds set up on some type of stand that had slot shaped like ¦_¦ at the top for the speakers to slide into. Anyone any ideas of what those stands would have been? Or any ideas of any other suitable stands?
  15. stevos

    Stands for Mission m7ds Speakers

    A couple of years ago i demo'ed a replacement centre speaker at sevenoaks, who had the m7ds set up on some type of stand that had slot shaped like ¦_¦ at the top for the speakers to slide into. Anyone any ideas of what those stands would have been?
  16. R

    MISSION M7ds

    can any one tell me if these are anygood for rear speakers cheers
  17. Matt

    Mounting Mission M7DS suggestions

    My living room is being replasters so i am taking the opertunity to get my Mission M7SD rear speakers mounted where i want them I am going to be putting the cable in the wall and then connecting them to the speakers. Because of the low profile i cannot use banana plugs so will either connect...
  18. P

    Stands for rears M7DS

    Hi i may be moving into rented accomidation soon so no drilling hoels in the walls ect ... What stands should i get for my rears (M7DS) they are fairly big so i'm thinking normal satelite stands won't cut it. I also want the stands to be fairly weighty for stability and dambting.
  19. R

    Mission M7DS in white?

    Hi. I've placed a wanted ad. in the classifieds for a pair of white Mission M7DS rear speakers. I've now suddenly got doubts whether Mission actually made them in this colour! Please could someone tell me if they did? Thank you, Andrew.
  20. E

    Where can I get some Mission M7DS speakers???

    Can anyone please tell me where I can buy a set of these speakers from? I have looked everywhere and fleabay and still no luck??? :( :( :( Help.... :(
Back
Top Bottom