I don't have any personal experience of building my own house, but building costs varies depending on where abouts in the UK you want to build and how much the land costs. Have a look locally at the new build house prices by the house construction companies, you might save yourself about 30%, depending on what kind of materials you use.
There are a few UK web sites for Self Builds, eg
http://www.buildstore.co.uk/
To self build you will need to research quite alot on house construction, and to have good project management skills.
The other option is to employ an architect to do most of the work for you, ie, draw up floor plans, elevations, apply for planning permission, draw up detailed construction plans, produce an NBS specification, apply for building control, help you find a constuction company, liase with the builders etc. they will typically charge about 10% +VAT of the final construction costs.
Anyone a Quantity Surveyor here? They coud tell you the going rate or your local library might have a book called Spon's Architects and Builders price book, which should list prices per sqaure metre.
Although with regards to construction costs budget £X amount, and add an extra 20% extra, just to be on the safe side. Best of luck with your decision.
Regards,
CML