You're all missing the point - admittedly the OP wasn't very clear.
What he means is if you have two single gang Lutron rania controls in one room controlling two independent lighting circuits, can you control them individually by remote? The answer appears to be no because both switches respond to the same IR command and there is no way to reprogramming one of them to another code.
Likewise, with two two-gang dimmers in one room the first gang of both would go on and off together by remote, and the second gang of both would go on and off together by remote.
I didn't realise this, I assumed given the price they would be programmable like the Varilights. I agree what a ridiculous limitation for such an expensive range! If I hadn't just read this thread I may have just gone and made a very expensive mistake!
I'm having nothing but frustration looking for IR controlled dimmers. The Varilights have the stupid one-button design, and now I find the Lutrons aren't programmable! Do the people who design these things not actually use them????