Yes, Ebay (a rather slow loading annoying site) optimises pictures so the pages load faster.
You can optimise for web in PhotoChop (Edit Menu). For most web apps you want around 30-50kb , 72 dpi file sizes.
If you can find out the sizes ebay work to, optimise yourself to those sizes, set a small file size. PS will do a better job

Dont set 300 dpi on your pics, thats print res only