I decided to have a crack at this after reading this thread.
Finally finished it.
In general, I found it to be a much easier read than I had anticipated. There were, however, a couple of things hampering progress.
The start was a little bit confusing. There are so many characters introduced (most of them having alternative names) that I lost track of who was who. Also, the similarity of some of the names didn't help (Kuragin/Karagin). I found that at the end of Book 1/Part 1, I had to go back and start again, just to get a clearer picture of who everyone was.
The first 1400 pages were fine, but the last 40 took me about a month to get through. I thought that skipping this last chunk would be cheating.